A supersaturation wave of protein crystallization
نویسندگان
چکیده
منابع مشابه
Protein crystallization
This essay is about the crystallization of proteins. Since the first published observation of crystallizing proteins about 160 years ago, protein crystal growth has developed into an extensive research field with many applications, for instance in the pharmaceutical industry. In this report, an overview of the unique physical-chemical characteristics of protein molecules, their properties in so...
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Fusion proteins can be used directly in protein crystallization to assist crystallization in at least two different ways. In one approach, the `heterologous fusion-protein approach', the fusion partner can provide additional surface area to promote crystal contact formation. In another approach, the `fusion of interacting proteins approach', protein assemblies can be stabilized by covalently li...
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Currently, x-ray crystallography is the primary experimental tool employed to understand how proteins fold and assemble into well-defined structures. These diffraction methods critically depend the ability to produce high-purity crystal samples, but conventional crystallization processes are inherently slow and challenging to control. Here we explore a fundamentally different electrokinetically...
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The self-assembly of membrane proteins from solution into two-dimensional crystals is studied numerically using a continuum model proposed by Talanquer and Oxtoby (J. Chem. Phys. 109, 223 (1998)). Although the mean field theory presented here is only qualitatively accurate in two dimensions, we obtain the main features of the crystal nucleation process, such as the nucleation free energy barrie...
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ژورنال
عنوان ژورنال: Journal of Crystal Growth
سال: 2001
ISSN: 0022-0248
DOI: 10.1016/s0022-0248(01)01144-7